Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.39 |
| ▸ | KDM5A | P29375 | 4/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22245628 | 0.83 | KDM4E (0.56) | KDM4EASPHKDM8DHODHBCL2L1 | |
| SCHEMBL22245585 | 0.82 | KDM4E (0.48) | KDM4EASPHKDM8DHODHBCL2L1 | |
| SCHEMBL22245497 | 0.77 | DHODH (0.44) | KDM4EASPHKDM8DHODHBCL2L1 | |
| SCHEMBL28988558 | 0.77 | KDM4E (0.45) | KDM4EASPHKDM8DHODHBCL2L1 | |
| SCHEMBL3712467 | 0.77 | KDM4E (0.67) | KDM4EDHODHBCL2L1BADTDP1 | |
| SCHEMBL28988578 | 0.76 | KDM4E (0.43) | KDM4EASPHKDM8BCL2L1BAD | |
| SCHEMBL481041 | 0.75 | NAPRT (0.55) | KDM4EASPHKDM8TDP1KDM4C | |
| SCHEMBL22245516 | 0.75 | KDM4E (0.45) | KDM4EASPHKDM8DHODHBCL2L1 | |
| SCHEMBL23930207 | 0.73 | DHODH (0.43) | KDM4EDHODHBCL2L1BADKMO | |
| SCHEMBL28988572 | 0.73 | KDM4E (0.40) | KDM4EASPHKDM8DHODHBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003406-B | Heteroaryl ring nitroxide compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-116003406-A | Heteroaryl ring nitroxide compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2023-04-25 | — | — | CN | disclosed |
| EP-3892618-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020147705-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2020-07-23 | — | — | WO | disclosed |