Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.58 |
| ▸ | DHODH | Q02127 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912675 | 0.85 | KDM4E (0.77) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL31586013 | 0.85 | KDM4E (0.77) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL30108258 | 0.85 | PARP1 (0.47) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL28225056 | 0.85 | PARP1 (0.47) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL31676801 | 0.83 | KDM4E (0.67) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL22245628 | 0.83 | KDM4E (0.56) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL6924541 | 0.83 | KDM4E (0.67) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL14564497 | 0.83 | KDM4E (0.67) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL16536220 | 0.83 | KDM4E (0.67) | KDM4ETDP1NAPRTDHODHALDH1A1 | |
| SCHEMBL8304580 | 0.82 | KDM4E (0.53) | KDM4ETDP1NAPRTDHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | claimed |
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |