SCHEMBL22245653

SCHEMBL22245653

C=CC(=O)OCCOc1ccc(-c2ccc(C(=O)Oc3ccc(OC(=O)c4ccc(-c5ccc(OCCOC(C)=O)cc5)cc4)c(C)c3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.44
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
MAPT P10636 9/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KMT2A Q03164 1/20 0.37
KCNH2 Q12809 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
TP53 P04637 1/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301278 0.96 THRB (0.48) THRBPPARGPPARDPPARAMAPT
SCHEMBL20693285 0.95 PPARG (0.43) THRBPPARGPPARDPPARAMAPT
SCHEMBL21883822 0.94 THRB (0.44) THRBMAPTSMN1; SMN2TDP1L3MBTL1
SCHEMBL12172630 0.93 THRB (0.51) THRBPPARGPPARDPPARAMAPT
SCHEMBL24806405 0.92 THRB (0.43) THRBPPARGPPARDPPARAMAPT
SCHEMBL19605891 0.92 MAPT (0.41) THRBPPARGPPARDPPARAMAPT
SCHEMBL14038295 0.92 MAPT (0.41) THRBPPARGPPARDPPARAMAPT
SCHEMBL17070342 0.92 MAPT (0.41) THRBPPARGPPARDPPARAMAPT
SCHEMBL21883940 0.92 MAPT (0.41) THRBPPARGPPARDPPARAMAPT
SCHEMBL17301284 0.92 THRB (0.50) THRBMAPTSMN1; SMN2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634638-B2 Liquid crystal composition, reflective layer, method for producing reflective layer, and copolymer FUJIFILM CORPORATION (JP) 2023-04-25 US disclosed
US-20200231874-A1 LIQUID CRYSTAL COMPOSITION, REFLECTIVE LAYER, METHOD FOR PRODUCING REFLECTIVE LAYER, AND COPOLYMER FUJIFILM CORPORATION (JP) 2020-07-23 US disclosed