⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855810 | 0.79 | — | — | |
| SCHEMBL743897 | 0.71 | HDAC4 (0.42) | — | |
| SCHEMBL746138 | 0.70 | GAA (0.46) | — | |
| SCHEMBL6238602 | 0.70 | — | — | |
| SCHEMBL3371802 | 0.64 | — | — | |
| SCHEMBL8628324 | 0.63 | POLB (0.34) | — | |
| SCHEMBL10431180 | 0.61 | — | — | |
| SCHEMBL3021513 | 0.59 | — | — | |
| SCHEMBL1810308 | 0.59 | HCAR2 (0.61) | — | |
| SCHEMBL743959 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102558167-A | Thiazolidine derivant with GK and PPAR double excitation activity | INST MATERIA MEDICA CAMS | 2012-07-11 | — | — | CN | claimed |
| CN-102558149-A | Pyrimidine derivative, preparation method thereof, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2012-07-11 | — | — | CN | claimed |
| CN-1052675-A | Insecticides | CIBA GEIGY AG (CH) | 1991-07-03 | — | — | CN | claimed |
| JP-4117380-A | — | — | None | — | — | JP | disclosed |
| WO-2023233033-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2023-12-07 | — | — | WO | disclosed |
| US-20120329784-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC | 2012-12-27 | — | — | US | disclosed |
| EP-2523559-A1 | COMPOUNDS AND METHODS | GlaxoSmithKline LLC (US) | 2012-11-21 | — | — | EP | disclosed |
| CN-102791131-A | Compounds and methods | GLAXOSMITHKLINE LLC | 2012-11-21 | — | — | CN | disclosed |
| CN-102558167-A | Thiazolidine derivant with GK and PPAR double excitation activity | INST MATERIA MEDICA CAMS | 2012-07-11 | — | — | CN | disclosed |
| CN-102558149-A | Pyrimidine derivative, preparation method thereof, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2012-07-11 | — | — | CN | disclosed |
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-6011037-A | Thiazole derivatives with phosphodiesterase-inhibiting action | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-01-04 | — | — | US | disclosed |
| EP-0920426-A1 | NEW THIAZOLE DERIVATIVES WITH PHOSPHODIESTERASE-INHIBITING EFFECT | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998008830-A1 | THIAZOLE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE-IV | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998008841-A1 | NEW THIAZOLE DERIVATIVES WITH PHOSPHODIESTERASE-INHIBITING EFFECT | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-05 | — | — | WO | disclosed |
| CN-1028477-C | Microbicide composition containing thiazolyl-5-carboxamide derivatives | CIBA GEIGY AG (CH) | 1995-05-24 | — | — | CN | disclosed |
| US-5393766-A | Thiazolyl-5-carbonamide derviatives | CIBA-GEIGY CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| US-5210205-A | Plant fungicide, thiazolocarboxamides, N-cyanoalkyl- | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| JP-H04117380-A | PESTICIDAL COMPOSITION | CIBA GEIGY AG | 1992-04-17 | — | — | JP | disclosed |
| CN-1052675-A | Insecticides | CIBA GEIGY AG (CH) | 1991-07-03 | — | — | CN | disclosed |