SCHEMBL1810308

SCHEMBL1810308

O=C(O)c1cnc(C(=O)O)s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.61
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
GAA P10253 1/20 0.41
DAO P14920 6/20 0.38
GPR35 Q9HC97 2/20 0.38
PRKAB2 O43741 1/20 0.37
PRKAG1 P54619 1/20 0.37
PRKAA2 P54646 1/20 0.37
PRKAA1 Q13131 1/20 0.37
PRKAG3 Q9UGI9 1/20 0.37
PRKAG2 Q9UGJ0 1/20 0.37
PRKAB1 Q9Y478 1/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11597191 0.98 HCAR2 (0.59) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL600887 0.84 HCAR2 (0.61) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL27805851 0.84 HCAR2 (0.45) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL4019091 0.84 HCAR2 (0.55) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL17204603 0.84 HCAR2 (0.50) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL14164243 0.83 HCAR2 (0.50) HCAR2KDM4EALDH1A1GAAPRKAB2
SCHEMBL16198634 0.83
SCHEMBL24036436 0.81 HCAR2 (0.57) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL2202287 0.79 HDAC6 (0.54) HCAR2KDM4EALDH1A1GAADAO
SCHEMBL12510199 0.79 HCAR2 (0.50) HCAR2KDM4EALDH1A1GAADAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9714320-B2 Process for preparing a high molecular weight heteroaromatic polyester or copolyester UHDE INVENTA-FISCHER GMBH (DE) 2017-07-25 US claimed
EP-2814864-A2 PROCESS FOR PREPARING A HIGH MOLECULAR WEIGHT HETEROAROMATIC POLYESTER OR COPOLYESTER Uhde Inventa-Fischer GmbH (DE) 2014-12-24 EP claimed
US-20140357808-A1 Process For Preparing A High Molecular Weight Heteroaromatic Polyester Or Coplyester UHDE INVENTA-FISCHER GMBH (DE) 2014-12-04 US claimed
CN-104136485-A PROCESS FOR PREPARING A HIGH MOLECULAR WEIGHT HETEROAROMATIC POLYESTER OR COPOLYESTER UHDE INVENTA FISCHER GMBH 2014-11-05 CN claimed
WO-2013120989-A2 PROCESS FOR PREPARING A HIGH MOLECULAR WEIGHT HETEROAROMATIC POLYESTER OR COPOLYESTER UHDE INVENTA-FISCHER GMBH (DE) 2013-08-22 WO claimed
WO-2023192645-A2 METAL-ORGANIC CAGES, METHODS OF MAKING, AND METHODS OF USE THEREOF VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2023-10-05 WO disclosed
EP-3885340-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2021-09-29 EP disclosed
US-20210283574-A1 Multivariate and other metal-organic frameworks, and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-09-16 US disclosed
US-11046713-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2021-06-29 US disclosed
EP-3434731-B1 RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE ZEON CORP (JP) 2021-06-09 EP disclosed
EP-3369732-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2021-05-26 EP disclosed
CN-108779317-B Resin composition, resin film, and electronic component 日本瑞翁株式会社 2021-04-16 CN disclosed
US-4137234-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-01-30 US disclosed
US-4137237-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-01-30 US disclosed
US-4070475-A THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1978-01-24 US disclosed
US-4024271-A INHIBITORS OF HISTAMINE ACTIVITY SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-05-17 US disclosed
US-4022797-A PHARMACEUTICALS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-05-10 US disclosed
US-4018931-A INHIBITION OF H-2 HISTAMINE RECEPTORS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-04-19 US disclosed
US-3950353-A HISTAMINE INHIBITORS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-04-13 US disclosed
US-3950333-A HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210283574-A1 Multivariate and other metal-organic frameworks, and uses thereof AQP3, AQP4, AQP1 HCAR2 2235/4885KDM4E 4017/4885ALDH1A1 3384/4885
US-11046713-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG HCAR2 364/4885KDM4E 2389/4885ALDH1A1 570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.