SCHEMBL2224754

SCHEMBL2224754

COc1ccc(/C=C/C(=O)OCCCCCCO)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.67
TTR P02766 1/20 0.65
FDPS P14324 2/20 0.62
ACHE P22303 4/20 0.59
BCHE P06276 3/20 0.59
MET P08581 2/20 0.59
NFE2L2 Q16236 1/20 0.58
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
MAPT P10636 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALOX5 P09917 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2224756 1.00 APP (0.67) APPTTRFDPSACHEBCHE
SCHEMBL2638677 0.91 FDPS (0.67) APPFDPSACHEBCHEKDM4E
SCHEMBL2638679 0.91 FDPS (0.67) APPFDPSACHEBCHEKDM4E
SCHEMBL2282088 0.91 FDPS (0.67) APPFDPSACHEBCHEKDM4E
SCHEMBL19358969 0.90 APP (0.69) APPTTRFDPSACHEBCHE
SCHEMBL19358971 0.90 APP (0.69) APPTTRFDPSACHEBCHE
SCHEMBL10061433 0.89 TTR (0.63) APPTTRFDPSACHEBCHE
SCHEMBL16001635 0.87 FDPS (0.59) APPTTRFDPSACHEBCHE
SCHEMBL6873903 0.86 FDPS (0.81) APPFDPSACHEBCHENFE2L2
SCHEMBL6873896 0.86 FDPS (0.81) APPFDPSACHEBCHENFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362151-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2013-01-29 US disclosed
EP-2513157-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS Li, Chunhong (US) 2012-10-24 EP disclosed
WO-2011084546-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS LI CHUNHONG (US) 2011-07-14 WO disclosed
US-20100305230-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2010-12-02 US disclosed
EP-0860455-B1 Photocrosslinkable polymers ROLIC AG (CH) 2008-06-04 EP disclosed
US-6632909-B2 Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. ROLIC AG (CH) 2003-10-14 US disclosed
US-20020061996-A1 Photocrosslinkable polymers BUCHECKER RICHARD (CH) 2002-05-23 US disclosed
EP-0860455-A2 Photocrosslinkable polymers Rolic AG (CH) 1998-08-26 EP disclosed