Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 4/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | STK25 | O00506 | 1/20 | 0.31 |
| ▸ | CIT | O14578 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248602 | 0.91 | FAAH (0.34) | FAAHMGLLTRPV1CACNA1HRET | |
| SCHEMBL22248606 | 0.91 | FAAH (0.34) | FAAHMGLLTRPV1CACNA1HRET | |
| Hydrochloric Acid SCHEMBL30276382 | 0.91 | FAAH (0.34) | FAAHMGLLTRPV1CACNA1HRET | |
| SCHEMBL25532400 | 0.89 | FAAH (0.36) | FAAHMGLLTRPV1CACNA1HRET | |
| SCHEMBL22254392 | 0.89 | FAAH (0.36) | FAAHTRPV1RETKDREPHX2 | |
| Hydrochloric Acid SCHEMBL30401077 | 0.89 | FAAH (0.36) | FAAHTRPV1RETKDREPHX2 | |
| Hydrochloric Acid SCHEMBL22233846 | 0.89 | FAAH (0.36) | FAAHTRPV1RETKDREPHX2 | |
| SCHEMBL22248722 | 0.83 | FAAH (0.35) | FAAHMGLLTRPV1RETKDR | |
| Hydrochloric Acid SCHEMBL30276478 | 0.82 | FAAH (0.35) | FAAHMGLLTRPV1RETKDR | |
| SCHEMBL22249242 | 0.81 | FAAH (0.34) | FAAHMGLLTRPV1RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |