Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16986605 | 0.88 | GLA (0.38) | SMN1; SMN2GLAALDH1A1LMNATSHR | |
| Hydrochloric Acid SCHEMBL2223570 | 0.87 | GLA (0.37) | SMN1; SMN2GLAALDH1A1LMNATSHR | |
| SCHEMBL16986606 | 0.82 | GLA (0.36) | SMN1; SMN2GLAALDH1A1TSHRHTR7 | |
| SCHEMBL16986598 | 0.81 | HTR6 (0.42) | SMN1; SMN2GLAALDH1A1TSHRHTR7 | |
| Hydrochloric Acid SCHEMBL2224896 | 0.81 | GLA (0.35) | SMN1; SMN2GLAALDH1A1TSHRHTR7 | |
| Hydrochloric Acid SCHEMBL2224778 | 0.81 | HTR6 (0.42) | SMN1; SMN2GLAALDH1A1TSHRHTR7 | |
| Hydrochloric Acid SCHEMBL2224259 | 0.77 | NAMPT (0.39) | SMN1; SMN2TSHRHTR6POLB | |
| SCHEMBL16986601 | 0.75 | BRD4 (0.43) | SMN1; SMN2GLAALDH1A1TSHRHTR7 | |
| Hydrochloric Acid SCHEMBL2224249 | 0.74 | POLB (0.43) | ALDH1A1LMNATSHRHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL2221121 | 0.74 | BRD4 (0.42) | SMN1; SMN2GLAALDH1A1TSHRHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | claimed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | claimed |
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | disclosed |