SCHEMBL22249166 — predicted protein targets

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	ROCK2	O75116	5/20	0.58

▸	GAA	P10253	1/20	0.39

▸	DPP4	P27487	2/20	0.37

▸	ALDH1A1	P00352	2/20	0.35

▸	CYP1A2	P05177	1/20	0.35

▸	CYP3A4	P08684	1/20	0.35

▸	CYP2D6	P10635	1/20	0.35

▸	CYP2C19	P33261	1/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	PDE2A	O00408	1/20	0.35

▸	KAT2B	Q92831	1/20	0.35

▸	AXL	P30530	1/20	0.34

▸	MERTK	Q12866	1/20	0.34

▸	KCNH2	Q12809	1/20	0.34

▸	MCHR1	Q99705	1/20	0.34

▸	CCR2	P41597	1/20	0.34

▸	ROCK1	Q13464	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22248688	0.89	ROCK2 (0.50)	ROCK2DPP4MCHR1
SCHEMBL22254223	0.89	ROCK2 (0.50)	ROCK2DPP4MCHR1
SCHEMBL22254490	0.88	ROCK2 (0.49)	ROCK2DPP4LMNAKCNH2MCHR1
SCHEMBL22248654	0.86	ROCK2 (0.50)	ROCK2ALDH1A1
SCHEMBL22254485	0.86	ROCK2 (0.51)	ROCK2KCNH2MCHR1
SCHEMBL22254166	0.83	ROCK2 (0.51)	ROCK2GAADPP4MCHR1
SCHEMBL22254159	0.83	ROCK2 (0.51)	ROCK2GAADPP4MCHR1
SCHEMBL25532196	0.83	ROCK2 (0.51)	ROCK2GAADPP4MCHR1
SCHEMBL22254182	0.82	ROCK2 (0.50)	ROCK2DPP4KCNH2MCHR1CCR2
SCHEMBL25532200	0.82	ROCK2 (0.50)	ROCK2DPP4KCNH2MCHR1CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020150372-A1	ANTIMICROBIAL COMPOUNDS AND METHODS	CURZA GLOBAL, LLC (US)	2020-07-23	—	—	WO	disclosed