Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248441 | 0.94 | ROCK2 (0.36) | ROCK2 | |
| SCHEMBL22248389 | 0.90 | ROCK2 (0.43) | ROCK2 | |
| SCHEMBL22248433 | 0.88 | ROCK2 (0.42) | ROCK2NOS3NOS1 | |
| SCHEMBL22248386 | 0.85 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL22248384 | 0.85 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL22248369 | 0.82 | MAOB (0.33) | ROCK2 | |
| SCHEMBL22248391 | 0.82 | ROCK2 (0.32) | ROCK2 | |
| SCHEMBL22249258 | 0.82 | MEN1 (0.30) | — | |
| SCHEMBL22249158 | 0.81 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL22254225 | 0.79 | ROCK2 (0.44) | ROCK2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |