Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22254226 | 0.88 | ROCK2 (0.54) | ROCK2CCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL25532079 | 0.88 | ROCK2 (0.54) | ROCK2CCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL25532193 | 0.85 | ROCK2 (0.47) | ROCK2 | |
| SCHEMBL22254190 | 0.84 | ROCK2 (0.49) | ROCK2TAAR1 | |
| SCHEMBL22254234 | 0.82 | ROCK2 (0.57) | ROCK2ROCK1 | |
| SCHEMBL22249179 | 0.79 | SLC6A4 (0.43) | ROCK2CCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL25554548 | 0.79 | SLC6A4 (0.43) | ROCK2CCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL25554537 | 0.79 | SLC6A4 (0.43) | ROCK2CCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL22248949 | 0.79 | SPHK1 (0.47) | ROCK2 | |
| SCHEMBL22254200 | 0.78 | PARP1 (0.40) | ROCK2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |