Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276499 | 0.90 | JAK1 (0.32) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL28694755 | 0.89 | NAMPT (0.36) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL30276645 | 0.89 | FAAH (0.34) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL22249200 | 0.89 | FAAH (0.34) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL22249207 | 0.88 | JAK1 (0.36) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL30276467 | 0.88 | JAK1 (0.36) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL30276619 | 0.85 | FAAH (0.34) | JAK1FAAHROCK2ENPP2 | |
| SCHEMBL30276394 | 0.85 | KCNK3 (0.38) | JAK1FAAHENPP2 | |
| SCHEMBL22248809 | 0.82 | JAK1 (0.36) | JAK1FAAH | |
| SCHEMBL30276507 | 0.82 | JAK1 (0.36) | JAK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |