Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19045066 | 1.00 | HDAC3 (0.32) | HDAC3HDAC1HDAC2SSTR4ARG1 | |
| SCHEMBL20418174 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL20417973 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL18418153 | 0.77 | CYP1A2 (0.33) | HDAC3HDAC1HDAC2SSTR4 | |
| SCHEMBL9965985 | 0.77 | PPP5C (0.36) | SMN1; SMN2 | |
| SCHEMBL16252754 | 0.77 | PPP5C (0.36) | SMN1; SMN2 | |
| SCHEMBL13735630 | 0.77 | PPP5C (0.36) | SMN1; SMN2 | |
| SCHEMBL18711709 | 0.76 | CHRNB2 (0.45) | HDAC3HDAC1HDAC2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20943290 | 0.75 | TDP1 (0.37) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20943288 | 0.75 | TDP1 (0.37) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |