Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
| ▸ | CCR8 | P51685 | 2/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21130135 | 0.85 | L3MBTL1 (0.58) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL862349 | 0.82 | L3MBTL1 (0.65) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL16110206 | 0.82 | CCR1 (0.46) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL31135899 | 0.82 | CCR1 (0.46) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL23847797 | 0.80 | HSP90AA1 (0.52) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL20666433 | 0.80 | HSP90AA1 (0.52) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL16132323 | 0.80 | CCR1 (0.44) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL25215813 | 0.78 | L3MBTL1 (0.43) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL31135889 | 0.78 | CCR1 (0.42) | HSP90AA1L3MBTL1NPC1CCR1CCR8 | |
| SCHEMBL25212506 | 0.78 | CCR1 (0.42) | HSP90AA1L3MBTL1NPC1CCR1CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150675-A1 | COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-07-23 | — | — | WO | disclosed |