Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | PRKX | P51817 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343187 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1LRRK2CDC7DAPK3 | |
| SCHEMBL21610985 | 0.82 | CHEK1 (0.46) | HSP90AA1HSP90AB1LRRK2CDC7DAPK3 | |
| SCHEMBL20588419 | 0.77 | HSP90AB1 (0.39) | HSP90AB1LRRK2CDC7DAPK3PRKD3 | |
| SCHEMBL16177859 | 0.77 | LRRK2 (0.57) | HSP90AA1HSP90AB1LRRK2ROCK1ROCK2 | |
| SCHEMBL31555854 | 0.71 | KDM4E (0.46) | — | |
| SCHEMBL2594685 | 0.70 | CHUK (0.40) | HSP90AA1HSP90AB1LRRK2CHUKNOTUM | |
| SCHEMBL23148057 | 0.67 | MAPK1 (0.32) | CHUK | |
| SCHEMBL29721790 | 0.67 | MAPK1 (0.32) | CHUK | |
| SCHEMBL20555173 | 0.64 | LRRK2 (0.50) | HSP90AA1HSP90AB1LRRK2CHUKTRPA1 | |
| SCHEMBL2316808 | 0.64 | CSNK2A1 (0.34) | LRRK2CDC7DAPK3PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240844-B2 | Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease | VORONOI, INC. (KR) | 2025-03-04 | — | — | US | disclosed |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO INC. (KR) | 2023-06-15 | — | — | US | disclosed |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO INC. (KR) | 2023-06-15 | — | — | US | disclosed |
| US-20220064161-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | VORONOI, INC. (KR) | 2022-03-03 | — | — | US | disclosed |
| US-20220064161-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | VORONOI, INC. (KR) | 2022-03-03 | — | — | US | disclosed |
| EP-3915986-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | Voronoi Inc. (KR) | 2021-12-01 | — | — | EP | disclosed |
| EP-3915985-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | Voronoi Co., Ltd. (KR) | 2021-12-01 | — | — | EP | disclosed |
| CN-113574057-A | Heteroaryl derivatives and pharmaceutical compositions containing the same as active ingredient | 株式会社沃若诺伊 | 2021-10-29 | — | — | CN | disclosed |
| WO-2020185044-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2020-09-17 | — | — | WO | disclosed |
| WO-2020149715-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | 주식회사 보로노이 | 2020-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240844-B2 | Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease | CLK1, CLK2, CLK3 | HSP90AA1 1061/4885HSP90AB1 1118/4885LRRK2 5/4885 |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | TTK, TTBK1, TTBK2 | HSP90AA1 1932/4885HSP90AB1 2049/4885LRRK2 509/4885 |
| US-20220064161-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | CLK1, CLK2, CLK3 | HSP90AA1 896/4885HSP90AB1 940/4885LRRK2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.