Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25532137 | 1.00 | ROCK2 (0.38) | ROCK2KDM4EALDH1A1MCHR1TRPM8 | |
| SCHEMBL25554064 | 1.00 | ROCK2 (0.38) | ROCK2KDM4EALDH1A1MCHR1TRPM8 | |
| SCHEMBL25532122 | 0.95 | ROCK2 (0.41) | ROCK2KDM4EALDH1A1TRPM8 | |
| SCHEMBL22254500 | 0.95 | ROCK2 (0.41) | ROCK2KDM4EALDH1A1TRPM8 | |
| SCHEMBL22254220 | 0.94 | ROCK2 (0.37) | ROCK2KDM4EALDH1A1MCHR1 | |
| SCHEMBL25532052 | 0.94 | ROCK2 (0.37) | ROCK2KDM4EALDH1A1MCHR1 | |
| SCHEMBL22254830 | 0.92 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL25554777 | 0.92 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL22254827 | 0.90 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL25532202 | 0.90 | ROCK2 (0.37) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |