Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25532123 | 1.00 | ROCK2 (0.38) | ROCK2HRH4HRH3MCHR1KCNH2 | |
| SCHEMBL22254243 | 0.92 | ROCK2 (0.40) | ROCK2HRH4HRH3MCHR1KCNH2 | |
| SCHEMBL22254496 | 0.91 | ROCK2 (0.43) | ROCK2HRH4HRH3MCHR1KCNJ1 | |
| SCHEMBL25532121 | 0.91 | ROCK2 (0.43) | ROCK2HRH4HRH3MCHR1KCNJ1 | |
| SCHEMBL22254217 | 0.89 | ROCK2 (0.38) | ROCK2HRH4HRH3MCHR1KCNJ1 | |
| SCHEMBL25532075 | 0.89 | ROCK2 (0.38) | ROCK2HRH4HRH3MCHR1KCNJ1 | |
| SCHEMBL25554777 | 0.87 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL22254830 | 0.87 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL22254228 | 0.84 | ROCK2 (0.39) | ROCK2HRH4HRH3MCHR1KCNJ1 | |
| SCHEMBL22254241 | 0.83 | ROCK2 (0.38) | ROCK2MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |