Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22254691 | 0.86 | DPP4 (0.32) | DPP4 | |
| SCHEMBL25540250 | 0.80 | GRM2 (0.36) | GRM2AGTR2DPP4LMNACYP2C19 | |
| SCHEMBL25530377 | 0.78 | GRM2 (0.35) | GRM2AGTR2DPP4LMNACYP2C19 | |
| SCHEMBL25530844 | 0.78 | GRM2 (0.35) | GRM2AGTR2DPP4LMNACYP2C19 | |
| SCHEMBL25530380 | 0.78 | GRM2 (0.35) | GRM2AGTR2DPP4LMNACYP2C19 | |
| SCHEMBL27607055 | 0.68 | KMT2A (0.33) | — | |
| SCHEMBL24029615 | 0.66 | MAPT (0.47) | DPP4HSD17B10 | |
| SCHEMBL22248565 | 0.66 | CHRM1 (0.40) | DPP4LMNAHSD17B10 | |
| SCHEMBL22255068 | 0.66 | MAPT (0.42) | LMNACYP2C19HSD17B10 | |
| SCHEMBL22255060 | 0.66 | MAPT (0.42) | LMNACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |