SCHEMBL24029615

SCHEMBL24029615

CN(C)C(=O)N1CCN(C(=O)C(C)(C)N)CC1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 3/20 0.37
TSHR P16473 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
DPP4 P27487 1/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 1/20 0.34
PKM P14618 1/20 0.34
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26551078 0.83 MAPT (0.50) MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL282864 0.80
SCHEMBL18849753 0.79 MEN1 (0.44) MAPTKMT2AMEN1ALDH1A1NPC1
SCHEMBL2171890 0.77 CYP1A2 (0.50) DPP4HTR1A
SCHEMBL26197814 0.77 DPP4 (0.38) KMT2AMEN1SMN1; SMN2ALDH1A1NPC1
SCHEMBL24029818 0.77 ALDH1A1 (0.55) KMT2AMEN1SMN1; SMN2ALDH1A1NPC1
SCHEMBL7926325 0.76 DPP4 (0.44) MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL2747052 0.76 CHRNB2 (0.37) MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL3678338 0.76 HRH3 (0.50) KMT2AMEN1DPP4
Hydrochloric Acid SCHEMBL15742309 0.75 CYP1A2 (0.48) DPP4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423775-B Aryl glucoside derivative, and preparation method and application thereof 上海喆邺生物科技有限公司 2024-11-22 CN disclosed
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed
CN-114423775-A Aryl glucoside derivatives, and preparation method and application thereof 上海喆邺生物科技有限公司 2022-04-29 CN disclosed
WO-2021227440-A1 A CLASS OF ARYL GLUCOSIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海喆邺生物科技有限公司 2021-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SLC5A1, SLC5A2, SLC10A1 MAPT 3821/4885KMT2A 2796/4885MEN1 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.