Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.55 |
| ▸ | FPR2 | P25090 | 3/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1880847 | 0.96 | GRM5 (0.58) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL15121190 | 0.93 | GRM5 (0.53) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL1580244 | 0.92 | FAAH (0.58) | GRM5FPR2FAAHCNR2CNR1 | |
| SCHEMBL1578607 | 0.90 | GRM5 (0.53) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL9914317 | 0.90 | GRM5 (0.53) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL1578200 | 0.89 | GRM5 (0.55) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL1581107 | 0.89 | GRM5 (0.52) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL1578678 | 0.89 | GRM5 (0.52) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL1578381 | 0.89 | GRM5 (0.52) | GRM5FPR2P2RX7NPC1GBA1 | |
| SCHEMBL2269766 | 0.89 | GRM5 (0.51) | GRM5FPR2P2RX7NPC1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | claimed |