Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 9/20 | 0.52 |
| ▸ | CHIT1 | Q13231 | 8/20 | 0.52 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.45 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967611 | 0.92 | CHIA (0.54) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL16360093 | 0.83 | HRH3 (0.53) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL25541904 | 0.83 | CHIA (0.55) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL1968987 | 0.78 | CHIA (0.54) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL27817743 | 0.76 | HTR2A (0.49) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL1242233 | 0.76 | TAAR1 (0.60) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL1969047 | 0.76 | TAAR1 (0.60) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL27817745 | 0.76 | CHIT1 (0.63) | CHIACHIT1CHI3L1CHI3L2GRIN2B | |
| SCHEMBL1967143 | 0.75 | GRIN2B (0.63) | CHIAGRIN2BTAAR1HTR2ASLC18A3 | |
| SCHEMBL1966648 | 0.73 | TAAR1 (0.47) | CHIACHIT1CHI3L1CHI3L2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |