Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263035 | 0.71 | MAOB (0.47) | ALDH1A1L3MBTL1CYP3A4TSHRTDP1 | |
| SCHEMBL25541871 | 0.70 | TP53 (0.38) | EPHX1TSHRACACBSLC6A4 | |
| SCHEMBL25531102 | 0.70 | TSHR (0.39) | TSHRACACBSLC6A4 | |
| SCHEMBL10285127 | 0.69 | ADH1A (0.38) | — | |
| SCHEMBL3085764 | 0.68 | HRH3 (0.74) | HRH4HRH3ALDH1A1PDE4AL3MBTL1 | |
| SCHEMBL24251170 | 0.68 | SLC6A4 (0.60) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL25541884 | 0.68 | TSHR (0.38) | EPHX1TSHRDPP4DPP8DPP9 | |
| SCHEMBL22255195 | 0.68 | TSHR (0.38) | EPHX1TSHRDPP4DPP8DPP9 | |
| SCHEMBL4570869 | 0.67 | ADH1A (0.43) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL13503176 | 0.67 | ADH1A (0.43) | ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |