Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 6/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256359 | 0.94 | PHLPP2 (0.43) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22256316 | 0.94 | PHLPP2 (0.43) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22256416 | 0.94 | PHLPP2 (0.43) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22413422 | 0.88 | THRB (0.45) | PHLPP2CYP2C9CYP1A2THRBHSD17B10 | |
| SCHEMBL22256362 | 0.87 | PHLPP2 (0.39) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22256266 | 0.87 | PHLPP2 (0.39) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22256305 | 0.85 | MEN1 (0.45) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22256302 | 0.85 | PHLPP2 (0.45) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22411683 | 0.85 | PHLPP2 (0.45) | PHLPP2PTPN11CYP2C9CYP1A2THRB | |
| SCHEMBL22413435 | 0.85 | PHLPP2 (0.45) | PHLPP2PTPN11CYP2C9CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370921-B2 | Reactive dye compound and preparation method and application thereof | Shanghai Kehua dyestuff Industry Co., Ltd. (CN) | 2022-06-28 | — | — | US | disclosed |
| US-10954392-B2 | Reactive navy to black dye composition and dye product thereof | ZHEJIANG KEYONG CHEMICAL CO., LTD. (CN) | 2021-03-23 | — | — | US | disclosed |
| US-20200283634-A1 | A REACTIVE NAVY TO BLACK DYE COMPOSITION AND DYE PRODUCT THEREOF | Shanghai Kehua dyestuff Industry Co., Ltd. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-20200231819-A1 | A REACTIVE DYE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | ZHEJIANG KEYONG CHEMICAL CO., LTD. (CN) | 2020-07-23 | — | — | US | disclosed |