Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24390854 | 0.90 | PDK2 (0.48) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL24531294 | 0.87 | KDM4E (0.52) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL22256463 | 0.87 | PDK2 (0.56) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL22256476 | 0.86 | PDK2 (0.47) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL22256472 | 0.86 | PDK2 (0.47) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL22256474 | 0.81 | PDK2 (0.43) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL69464 | 0.80 | SLC6A3 (0.67) | TSHRMAPTMEN1HTTMAPK10 | |
| SCHEMBL5968745 | 0.78 | PDK2 (0.56) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL24531546 | 0.78 | PDK2 (0.42) | PDK2TSHRMAPTMEN1HTT | |
| SCHEMBL15593174 | 0.77 | PDK2 (0.46) | PDK2MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020148303-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | WO | disclosed |