Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.61 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685346 | 0.98 | RARB (0.64) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL6687468 | 0.98 | RARB (0.64) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL6686529 | 0.98 | RARB (0.64) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL4186955 | 0.95 | RARB (0.56) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL9176105 | 0.91 | RARB (0.58) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL6684291 | 0.89 | RARB (0.48) | RARBHTR2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9398982 | 0.87 | RARB (0.68) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL10979477 | 0.86 | RARB (0.70) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL10975095 | 0.86 | RARB (0.70) | RARBRARARARGHTR2ARAB9A | |
| SCHEMBL14175167 | 0.86 | RARB (0.66) | RARBRARARARGHTR2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011920-B | Liquid-crystalline medium comprising thiophene derivatives | 默克专利股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| US-9868906-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9868906-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9714383-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-07-25 | — | — | US | disclosed |
| US-9714383-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-07-25 | — | — | US | disclosed |
| US-9714383-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-07-25 | — | — | US | disclosed |
| US-20160168463-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168463-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168463-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160137922-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
| US-5437815-A | Blending with ordinary liquid crystal compounds broadens practical temperature range of composition and produces an enlarged double refraction anisotropy | SEIKO EPSON CORPORATION (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0414230-B1 | Liquid crystal composition and liquid crystal device containing the same | SHARP KK (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5271867-A | Liquid crystal composition and liquid crystal device containing the same | SHARP KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0535635-A1 | Tolane derivative, liquid crystal composition containing the derivative, and liquid crystal display device using the composition | SEIKO EPSON CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0414230-A2 | Liquid crystal composition and liquid crystal device containing the same | SHARP KABUSHIKI KAISHA (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0407569-A1 | DIPHENYLETHANES | MERCK PATENT GmbH (DE) | 1991-01-16 | — | — | EP | disclosed |
| EP-0132377-B1 | COMPOUNDS CONTAINING A FLUOROBIPHENYLYL GROUP AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICE | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1988-06-29 | — | — | EP | disclosed |
| US-4696549-A | Compounds containing a fluorobiphenylyl group and their use in liquid crystal material and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1987-09-29 | — | — | US | disclosed |
| US-4594465-A | Compounds containing a fluorobiphenylyl group | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-06-10 | — | — | US | disclosed |
| EP-0132377-A2 | Compounds containing a fluorobiphenylyl group and their use in liquid crystal materials and device | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137922-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | VCL, LASP1, L1CAM | RARB 2084/4885RARA 979/4885RARG 1874/4885 |
| US-20160168463-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | NLK, NCAPD2, LASP1 | RARB 2356/4885RARA 1600/4885RARG 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.