Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222565 | 0.95 | RARB (0.61) | RARBNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL6687468 | 0.94 | RARB (0.64) | RARBNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL6685346 | 0.94 | RARB (0.64) | RARBNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL6686529 | 0.94 | RARB (0.64) | RARBNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL6684291 | 0.90 | RARB (0.48) | RARBNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL10975470 | 0.87 | RARB (0.61) | RARBRARARARGMPLS1PR1 | |
| SCHEMBL9176105 | 0.86 | RARB (0.58) | RARBNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL9662908 | 0.85 | RARB (0.59) | RARBRARARARGMPLS1PR1 | |
| SCHEMBL14175170 | 0.85 | RARB (0.59) | RARBRARARARGMPLS1PR1 | |
| SCHEMBL10986630 | 0.84 | RARB (0.58) | RARBRARARARGMPLS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126006-B1 | Liquid crystal compounds, liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-6737125-B2 | SUCH AS 8,9-DIFLUORO-7-(4-PENTYLPHENYL)-2-PROPYL-2,3-DIHYDRO-1H -CYCLOPENTA(A)NAPHTHALENE; FOR USE IN AUTOMOBILE INTERIORS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-05-18 | — | — | US | disclosed |
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | CLARIANT INTERNATIONAL LTD. | 2003-06-12 | — | — | US | disclosed |
| US-6569505-B2 | Holography | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2003-05-27 | — | — | US | disclosed |
| US-20020142108-A1 | Liquid crystal compounds, liquid crystal medium and liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-10-03 | — | — | US | disclosed |
| EP-1126006-A2 | Liquid crystal compounds, liquid crystal medium and liquid crystal display | MERCK PATENT GmbH (DE) | 2001-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | SCO2, CYP2F1, OGFOD1 | RARB 3320/4885NPC1 37/4885NFKB1 1620/4885 |
| US-20020142108-A1 | Liquid crystal compounds, liquid crystal medium and liquid crystal display | CDC25C, TEC, PLK1 | RARB 3418/4885NPC1 2218/4885NFKB1 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.