SCHEMBL2225784

SCHEMBL2225784

C[C@@](N)(I)C(=O)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 13/20 0.50
L3MBTL1 Q9Y468 3/20 0.46
ATM Q13315 2/20 0.46
TDP1 Q9NUW8 2/20 0.42
MAPT P10636 1/20 0.42
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442574 0.84 ELANE (0.53) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL15228348 0.82 ELANE (0.51) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL27554728 0.82 ELANE (0.51) ELANEL3MBTL1ATMTDP1MAPT
Hydrochloric Acid SCHEMBL8790691 0.82 ELANE (0.51) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL28308124 0.82 ELANE (0.51) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL27925255 0.81 ELANE (0.51) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL27925256 0.81 ELANE (0.51) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL2342588 0.79 ELANE (0.72) ELANEL3MBTL1ATMTDP1
SCHEMBL17892329 0.79 ELANE (0.49) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL18671920 0.78 ELANE (0.47) ELANEL3MBTL1ATMTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516455-A1 MODIFIED PORCINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES Ambrx, Inc. (US) 2012-10-31 EP disclosed
WO-2011087810-A1 MODIFIED PORCINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES AMBRX, INC. (US) 2011-07-21 WO disclosed