SCHEMBL6442574

SCHEMBL6442574

CC(C)(N)C(=O)Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 12/20 0.53
L3MBTL1 Q9Y468 3/20 0.49
ATM Q13315 2/20 0.49
ALDH1A1 P00352 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8790691 0.98 ELANE (0.51) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL15228348 0.86 ELANE (0.51) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL27554728 0.86 ELANE (0.51) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL2225784 0.84 ELANE (0.50) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL27925256 0.84 ELANE (0.51) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL27925255 0.84 ELANE (0.51) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL2342588 0.83 ELANE (0.72) ELANEL3MBTL1ATMTDP1
SCHEMBL17892329 0.82 ELANE (0.49) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL27578403 0.81 ELANE (0.49) ELANEL3MBTL1ATMALDH1A1TDP1
SCHEMBL28547058 0.81 ELANE (0.47) ELANEL3MBTL1ATMALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0931082-A4 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 1999-11-17 EP claimed
EP-0931082-A1 NODULISPORIC ACID DERIVATIVES Merck & Co., Inc. (a New Jersey corp.) (US) 1999-07-28 EP claimed
WO-1998012196-A1 NODULISPORIC ACID DERIVATIVES MERCK & CO., INC. (US) 1998-03-26 WO claimed
US-4443548-A CULTURES, HYDROLASES, DL-ALPHA-METHYLPHENYLALANINE AMIDE UBE INDUSTRIES, LTD. (JP) 1984-04-17 US claimed
US-20050004288-A1 Resin composition, composition for solder resist, and cured article obtained therefrom NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-06 US disclosed
EP-1416003-A1 RESIN COMPOSITION, COMPOSITION FOR SOLDER RESIST, AND CURED ARTICLE OBTAINED THEREFROM Nippon Kayaku Kabushiki Kaisha (JP) 2004-05-06 EP disclosed
EP-0931082-B1 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 2003-03-19 EP disclosed
US-6221894-B1 ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS. MERCK & CO., INC. 2001-04-24 US disclosed
EP-0931082-A4 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 1999-11-17 EP disclosed
US-5962499-A ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS MERCK & CO., INC. (US) 1999-10-05 US disclosed
EP-0931082-A1 NODULISPORIC ACID DERIVATIVES Merck & Co., Inc. (a New Jersey corp.) (US) 1999-07-28 EP disclosed
WO-1998012196-A1 NODULISPORIC ACID DERIVATIVES MERCK & CO., INC. (US) 1998-03-26 WO disclosed
US-4443548-A CULTURES, HYDROLASES, DL-ALPHA-METHYLPHENYLALANINE AMIDE UBE INDUSTRIES, LTD. (JP) 1984-04-17 US disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP disclosed