SCHEMBL22257940

SCHEMBL22257940

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3sc3cc(-c5ccc6c(c5)c5cc7sc8ccccc8c7cc5n6-c5ccccc5)ccc34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
PRKDC P78527 2/20 0.32
LIMK1 P53667 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25474995 0.97 ALOX5 (0.38) ALOX5PRKDCLIMK1
SCHEMBL22257742 0.96 ALOX5 (0.37) ALOX5PRKDCLIMK1
SCHEMBL22257999 0.94 ALOX5 (0.42) ALOX5PRKDCLIMK1
SCHEMBL23947256 0.94 ALOX5 (0.36) ALOX5PRKDCLIMK1
SCHEMBL22258043 0.93 ALOX5 (0.40) ALOX5PRKDCLIMK1
SCHEMBL23948021 0.93 ALOX5 (0.38) ALOX5PRKDCLIMK1
SCHEMBL22257964 0.93 ALOX5 (0.38) ALOX5PRKDCLIMK1
SCHEMBL23948017 0.92 ALOX5 (0.36) ALOX5PRKDCLIMK1
SCHEMBL22258047 0.92 ALOX5 (0.36) ALOX5PRKDCLIMK1
SCHEMBL22022430 0.91 KDM4E (0.38) ALOX5PRKDCLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 ALOX5 1694/4885PRKDC 3825/4885LIMK1 4096/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 ALOX5 1694/4885PRKDC 3825/4885LIMK1 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.