Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236157 | 0.84 | EPHX1 (0.53) | EPHX1L3MBTL1CA12CA1CA2 | |
| SCHEMBL8215065 | 0.79 | DYRK1A (0.41) | EPHX2DYRK1APKMKDM4EALDH1A1 | |
| SCHEMBL1286744 | 0.79 | DYRK1A (0.41) | EPHX2DYRK1APKMKDM4EALDH1A1 | |
| SCHEMBL22236156 | 0.78 | SMYD3 (0.36) | EPHX2EPHX1L3MBTL1GSK3BDYRK1A | |
| SCHEMBL22258241 | 0.77 | EPHX1 (0.46) | EPHX1GSK3BDYRK1APKMKDM4E | |
| SCHEMBL24710064 | 0.73 | CDK14 (0.49) | GSK3BDYRK1A | |
| SCHEMBL1286738 | 0.72 | L3MBTL1 (0.35) | EPHX2L3MBTL1GSK3BDYRK1APKM | |
| SCHEMBL8222280 | 0.72 | L3MBTL1 (0.35) | EPHX2L3MBTL1GSK3BDYRK1APKM | |
| SCHEMBL8219219 | 0.71 | CCR8 (0.57) | L3MBTL1PKMKDM4EALDH1A1LMNA | |
| SCHEMBL8263051 | 0.71 | CDK14 (0.52) | L3MBTL1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |