Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498374 | 1.00 | THRB (0.36) | THRBSYKSSTR4NFKB1NFKB2 | |
| SCHEMBL22235217 | 0.94 | THRB (0.36) | THRBSYKSSTR4NFKB1NFKB2 | |
| SCHEMBL18786676 | 0.75 | PDPK1 (0.39) | THRBSYKNFKB1NFKB2RELA | |
| SCHEMBL18085719 | 0.75 | SSTR4 (0.36) | SSTR4PDPK1 | |
| SCHEMBL24389026 | 0.75 | SSTR4 (0.44) | SYKSSTR4PDPK1 | |
| SCHEMBL1181827 | 0.74 | SSTR4 (0.36) | SSTR4PDPK1 | |
| SCHEMBL6059213 | 0.74 | CYP2C19 (0.41) | SYKNFKB1NFKB2RELA | |
| SCHEMBL22235219 | 0.72 | AAK1 (0.35) | THRBSYK | |
| SCHEMBL22958315 | 0.72 | PDPK1 (0.34) | SYKSSTR4PDPK1 | |
| SCHEMBL29726252 | 0.72 | PDPK1 (0.34) | SYKSSTR4PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150626-A1 | IMIDAZO[1,2-A]PYRIDINYL DERIVATIVES AS IRAK4 INHIBITORS | BIOGEN MA INC. (US) | 2020-07-23 | — | — | WO | disclosed |