Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22259734 | 0.82 | SMN1; SMN2 (0.41) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL22259790 | 0.68 | — | — | |
| SCHEMBL22236262 | 0.66 | TP53 (0.37) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL22236064 | 0.65 | TP53 (0.39) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL22236100 | 0.62 | MAPT (0.34) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL13444589 | 0.60 | ACHE (0.46) | MEN1MAPTMAPK1KMT2AHPGD | |
| SCHEMBL24357492 | 0.58 | MAPT (0.60) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL12533981 | 0.57 | KMT2A (0.64) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL22016467 | 0.56 | POLB (0.37) | MAPK1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL19393174 | 0.56 | IDO1 (0.41) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | disclosed |