Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781321 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL190976 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL1972348 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL1713696 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL1977849 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL190977 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL30693235 | 1.00 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL1892809 | 0.90 | SLC6A4 (0.47) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL2354780 | 0.90 | SLC6A4 (0.47) | SLC6A3SLC6A4SLC6A2RORCF10 | |
| SCHEMBL1974759 | 0.90 | SLC6A4 (0.47) | SLC6A3SLC6A4SLC6A2RORCF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513052-A1 | PYRROLIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011085886-A1 | PYRROLIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-07-21 | — | — | WO | disclosed |