Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | CALML3 | P27482 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SDHA | P31040 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166248 | 0.85 | MAOA (0.58) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6024297 | 0.85 | MAOA (0.58) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3166255 | 0.85 | MAOA (0.58) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL30061895 | 0.84 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6022852 | 0.82 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6022851 | 0.82 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL22261645 | 0.82 | MAOA (0.39) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14386911 | 0.80 | BPTF (0.43) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6023931 | 0.80 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6023927 | 0.80 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635307-B1 | PHARMACEUTICAL COMPOSITIONS | MELINTA SUBSIDIARY CORP (US) | 2020-07-29 | — | — | EP | claimed |