Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187804 | 1.00 | KCNA3 (0.58) | KCNA3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8220314 | 0.91 | KCNA3 (0.56) | KCNA3 | |
| SCHEMBL8188731 | 0.81 | KCNA3 (0.58) | KCNA3OPRL1 | |
| SCHEMBL14305103 | 0.79 | MEN1 (0.59) | — | |
| SCHEMBL8387371 | 0.75 | OPRM1 (0.47) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL9065208 | 0.74 | OPRM1 (0.65) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL3561518 | 0.74 | AKR1C1 (0.54) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL9396812 | 0.74 | KMT2A (0.56) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL11721858 | 0.74 | AKR1C1 (0.54) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL503892 | 0.73 | OPRM1 (0.73) | KCNA3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914246-A1 | LOCAL ANESTHETIC FOR THE TREATMENT OF NEUROLOGICAL SYMPTOMS RESULTING FROM BRAIN DYSFUNCTIONS | ICM (Institut du Cerveau et de la Moelle Épinière) (FR) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020152212-A1 | LOCAL ANESTHETIC FOR THE TREATMENT OF NEUROLOGICAL SYMPTOMS RESULTING FROM BRAIN DYSFUNCTIONS | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2020-07-30 | — | — | WO | disclosed |