Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063145 | 0.82 | CACNA1I (0.34) | CARM1PRMT6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1063146 | 0.82 | CACNA1I (0.34) | CARM1PRMT6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22265158 | 0.79 | BCHE (0.51) | MEN1KMT2ABCHEF2KCNH2 | |
| SCHEMBL2860573 | 0.76 | DAO (0.41) | MAOBKCNH2CYP2C19 | |
| SCHEMBL2860576 | 0.76 | DAO (0.41) | MAOBKCNH2CYP2C19 | |
| SCHEMBL17769191 | 0.75 | SCN8A (0.39) | CARM1PRMT6BCHEALDH1A1 | |
| SCHEMBL14157203 | 0.74 | GRIA4 (0.46) | NPC1RAB9ASMN1; SMN2LMNAKCNH2 | |
| SCHEMBL14975405 | 0.74 | TAAR1 (0.52) | CYP1A2CYP2C19 | |
| SCHEMBL3232650 | 0.74 | TAAR1 (0.52) | CYP1A2CYP2C19 | |
| SCHEMBL14157207 | 0.74 | GRIA4 (0.46) | NPC1RAB9ASMN1; SMN2LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914351-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | Nodthera Limited (GB) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020152361-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-07-30 | — | — | WO | disclosed |