SCHEMBL22265286

SCHEMBL22265286

Cc1cc2c(cc1C)OC(C)(C)C2

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.35
IRAK4 Q9NWZ3 11/20 0.34
TSHR P16473 2/20 0.32
PKM P14618 1/20 0.32
DHFR P00374 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19046335 0.84 ALDH1A1 (0.42) ALDH1A1MAPTKDM4EIRAK4PKM
SCHEMBL19046371 0.84 CYP3A4 (0.37) ALDH1A1MAPTKDM4EIRAK4TSHR
SCHEMBL19046422 0.80 IRAK4 (0.44) ALDH1A1MAPTKDM4EIRAK4
SCHEMBL19045416 0.77 IRAK4 (0.43) ALDH1A1MAPTIRAK4GAA
SCHEMBL19030775 0.77 ALDH1A1 (0.35) ALDH1A1MAPTKDM4EIRAK4TSHR
SCHEMBL19045869 0.75 IRAK4 (0.55) IRAK4
SCHEMBL12035985 0.75 MAPT (0.41) ALDH1A1MAPTKDM4EHTTIRAK4
SCHEMBL21363752 0.75 CYP3A4 (0.37) ALDH1A1MAPTKDM4ETSHRGAA
SCHEMBL12180466 0.75 KDM4E (0.38) ALDH1A1MAPTKDM4EHTTIRAK4
SCHEMBL19046440 0.74 IRAK4 (0.46) IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020153769-A2 METHOD FOR PRODUCING HEAVY OIL WITH REDUCED ODOR INDUCTION AND HARMFUL VAPOR, AND SYSTEM THEREFOR 한국화학연구원 2020-07-30 WO disclosed