SCHEMBL222667

SCHEMBL222667

On1cnc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.54
HTT P42858 2/20 0.52
FGFR1 P11362 2/20 0.50
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
STAT6 P42226 1/20 0.48
POLB P06746 2/20 0.47
TNF P01375 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
EGLN3 Q9H6Z9 1/20 0.46
MAPK1 P28482 1/20 0.45
ATM Q13315 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6097684 0.98 TDP1 (0.52) TDP1HTTFGFR1LMNASMN1; SMN2
Sulfuric Acid SCHEMBL16346886 0.90 TDP1 (0.46) TDP1HTTFGFR1LMNASMN1; SMN2
Guanidine SCHEMBL4196962 0.90 TDP1 (0.46) TDP1HTTFGFR1LMNASMN1; SMN2
Pyrimidine SCHEMBL5798167 0.88 TDP1 (0.44) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL2489876 0.78 TDP1 (0.56) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL7196401 0.75 TDP1 (0.58) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL17265864 0.72 FGFR1 (0.35) FGFR1LMNAPOLBHSD17B10
SCHEMBL8668369 0.71 TDP1 (0.54) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL5399 0.71 TDP1 (0.59) TDP1HTTLMNASMN1; SMN2POLB
SCHEMBL9062626 0.71 TDP1 (0.54) TDP1HTTFGFR1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646423-A1 PEPTIDE SYNTHESIS METHOD INVOLVING STERICALLY HINDERED TRI-TERT-BUTYL-TRYPTOPHAN (TBT) RESIDUE Amicoat AS (NO) 2025-11-12 EP claimed
US-20250144226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2025-05-08 US claimed
WO-2025013869-A1 FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF ダイキン工業株式会社 2025-01-16 WO claimed
CN-118530332-A Preparation method of pramlintide 南京羚诺生物医药技术研究院有限公司 2024-08-23 CN claimed
WO-2024146948-A1 PEPTIDE SYNTHESIS METHOD INVOLVING STERICALLY HINDERED TRI-TERT-BUTYL-TRYPTOPHAN (TBT) RESIDUE AMICOAT AS (NO) 2024-07-11 WO claimed
CN-118142356-A Method for preparing ultrathin metal-organic framework film by steam-assisted in-situ conversion and separation application thereof 中国科学院大连化学物理研究所 2024-06-07 CN claimed
CN-114457511-A Wormwood non-woven fabric mixing equipment and production method of spun-bonded wormwood non-woven fabric 上海那博新材料科技有限公司 2022-05-10 CN claimed
US-20220127311-A1 CELL FACTORIES FOR IMPROVED PRODUCTION OF COMPOUNDS AND PROTEINS DEPENDENT ON IRON SULFUR CLUSTERS BIOSYNTIA APS (DK) 2022-04-28 US claimed
EP-2737042-B2 WASHING OR CLEANING METHOD WITH ELECTROCHEMICALLY ACTIVATABLE MEDIATOR COMPOUND HENKEL AG & CO KGAA (DE) 2022-04-06 EP claimed
EP-3911666-A1 CELL FACTORIES FOR IMPROVED PRODUCTION OF COMPOUNDS AND PROTEINS DEPENDENT ON IRON SULFUR CLUSTERS Biosyntia ApS (DK) 2021-11-24 EP claimed
WO-1995029920-A1 KHELLACTONE DERIVATIVES AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AND IMMUNOSTIMULATING AGENTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-11-09 WO claimed
WO-1995024383-A1 OXIME DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-14 WO claimed
EP-0509717-A2 New herbicidal compositions RHONE POULENC AGRICULTURE LTD. (GB) 1992-10-21 EP claimed
EP-0287806-B1 RUBBER COMPOSITIONS MODIFIED WITH HYDROXY-BENZIMIDAZOLE OXIDES THE FIRESTONE TIRE & RUBBER COMPANY (US) 1992-10-14 EP claimed
EP-0508800-A1 New Herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1992-10-14 EP claimed
US-5084571-A Colorfast heat resistant cyan color for photography FUJI PHOTO FILM CO., LTD. (JP) 1992-01-28 US claimed
EP-0287806-A1 Rubber compositions modified with hydroxy-benzimidazole oxides THE FIRESTONE TIRE & RUBBER COMPANY (US) 1988-10-26 EP claimed
US-4762870-A TIRES, HOSES, BELTS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1988-08-09 US claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250144226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE CLN6, CACYBP, CREBBP TDP1 552/4885HTT 928/4885FGFR1 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.