Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389268 | 0.84 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL7841838 | 0.84 | AGER (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL9903762 | 0.82 | FGFR1 (0.58) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL1136897 | 0.82 | TDP1 (0.43) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL4553023 | 0.81 | TDP1 (0.46) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL369486 | 0.80 | TDP1 (0.41) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL29991297 | 0.80 | GAA (0.47) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL9449531 | 0.80 | TDP1 (0.44) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL739312 | 0.80 | GAA (0.47) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL7043858 | 0.78 | TDP1 (0.43) | TDP1HTTCYP11B1CYP11B2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586357-B1 | Stereospecific catalysts; enantioselective reduction; transition metal complexes | CHEMI S.P.A. (IT) | 2003-07-01 | — | — | US | claimed |
| EP-0770085-B1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI SPA (IT) | 1999-09-22 | — | — | EP | claimed |
| EP-0770085-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.p.A. (IT) | 1997-05-02 | — | — | EP | claimed |
| WO-1996001831-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.P.A. (IT) | 1996-01-25 | — | — | WO | claimed |
| CN-106046057-B | N-heterocyclic carbene metal coordination polymer, preparation method thereof and application of N-heterocyclic carbene metal coordination polymer as catalyst | 复旦大学 | 2020-01-10 | — | — | CN | disclosed |
| CN-102177141-B | bis-1H-benzimidazoles as hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | disclosed |
| CN-102177141-A | bis-1H-benzimidazoles as hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-09-07 | — | — | CN | disclosed |
| US-6586357-B1 | Stereospecific catalysts; enantioselective reduction; transition metal complexes | CHEMI S.P.A. (IT) | 2003-07-01 | — | — | US | disclosed |
| US-6297387-B1 | AND THEIR USE AS CHIRAL CATALYSTS IN STEREOCONTROLLED REACTIONS, SUCH AS DIASTEREO- AND ENANTIOSELECTIVE REDUCTION REACTIONS, | ITALFARMACO SUD S.P.A. (IT) | 2001-10-02 | — | — | US | disclosed |
| US-6133191-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-10-17 | — | — | US | disclosed |
| US-6077958-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-06-20 | — | — | US | disclosed |
| EP-0770085-B1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI SPA (IT) | 1999-09-22 | — | — | EP | disclosed |
| US-5907045-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 1999-05-25 | — | — | US | disclosed |
| EP-0770085-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.p.A. (IT) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001831-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.P.A. (IT) | 1996-01-25 | — | — | WO | disclosed |