SCHEMBL22266752

SCHEMBL22266752

CO[C@H]1O[C@H](C=O)[C@@H](OCc2ccccc2)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 2/20 0.47
SSTR5 P35346 2/20 0.43
SSTR1 P30872 1/20 0.43
SSTR2 P30874 1/20 0.43
SSTR4 P31391 1/20 0.43
SSTR3 P32745 1/20 0.43
LGALS3 P17931 2/20 0.41
BCHE P06276 4/20 0.41
SLC6A2 P23975 1/20 0.41
PDPK1 O15530 2/20 0.40
MTOR P42345 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21706803 0.88 SSTR5 (0.47) LGALS8SSTR5SSTR1SSTR2SSTR4
SCHEMBL23914008 0.86 SSTR1 (0.53) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL9745334 0.86 SSTR1 (0.53) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13387386 0.86 SSTR1 (0.53) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL1117738 0.83 PDPK1 (0.44) LGALS8BCHESLC6A2PDPK1MTOR
SCHEMBL3825138 0.82 LGALS8 (0.50) LGALS8SSTR5SSTR1SSTR2SSTR4
SCHEMBL3827358 0.82 LGALS8 (0.50) LGALS8SSTR5SSTR1SSTR2SSTR4
SCHEMBL22212491 0.81 LGALS8 (0.49) LGALS8SSTR5SSTR1SSTR2SSTR4
SCHEMBL16148039 0.79 PDPK1 (0.45) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL31103781 0.79 PDPK1 (0.45) SSTR5SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723754-B2 2′,4′-bridged nucleosides for HCV infection IDENIX PHARMACEUTICALS LLC (US) 2020-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10723754-B2 2′,4′-bridged nucleosides for HCV infection SLC29A1, SLC28A1, SLC29A2 LGALS8 3560/4885SSTR5 4359/4885SSTR1 3217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.