⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501652 | 0.71 | — | — | |
| SCHEMBL1698642 | 0.71 | PIK3CD (0.37) | — | |
| SCHEMBL20936293 | 0.68 | — | — | |
| SCHEMBL22268216 | 0.64 | — | — | |
| SCHEMBL19754397 | 0.63 | ACHE (0.38) | — | |
| SCHEMBL24728918 | 0.62 | — | — | |
| SCHEMBL25081718 | 0.62 | — | — | |
| SCHEMBL22648379 | 0.61 | PIK3CD (0.36) | — | |
| SCHEMBL13684170 | 0.61 | PIK3CD (0.39) | — | |
| SCHEMBL10312571 | 0.60 | PIK3CD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723733-B2 | Hepatitis B antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2020-07-28 | — | — | US | disclosed |