SCHEMBL22268458

SCHEMBL22268458

N#Cc1ccc(-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 2/20 0.38
ABCG2 Q9UNQ0 2/20 0.38
ABCB1 P08183 1/20 0.38
MYC P01106 1/20 0.38
PTGER4 P35408 1/20 0.38
GABRA1 P14867 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
CLK4 Q9HAZ1 2/20 0.36
JAK2 O60674 1/20 0.36
PRKD3 O94806 1/20 0.36
ABL1 P00519 1/20 0.36
EGFR P00533 1/20 0.36
ERBB2 P04626 1/20 0.36
LCK P06239 1/20 0.36
CDK1 P06493 1/20 0.36
CSF1R P07333 1/20 0.36
LYN P07948 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22268545 0.99 ABCG2 (0.40) ALDH1A3ABCG2ABCB1MYCPTGER4
SCHEMBL22268459 0.97 ALDH1A3 (0.40) ALDH1A3ABCG2ABCB1MYCGABRA1
SCHEMBL22268546 0.96 MYC (0.42) ALDH1A3ABCG2ABCB1MYCPTGER4
SCHEMBL22268553 0.95 ALDH1A3 (0.39) ALDH1A3ABCG2ABCB1MYCPTGER4
SCHEMBL22268464 0.94 ABCG2 (0.40) ALDH1A3ABCG2ABCB1MYCPTGER4
SCHEMBL22268538 0.93 ABCG2 (0.43) ALDH1A3ABCG2ABCB1MYCGABRA1
SCHEMBL22268544 0.93 ABCG2 (0.40) ALDH1A3ABCG2ABCB1MYCPTGER4
SCHEMBL21742003 0.92 PTGER4 (0.39) ALDH1A3ABCG2ABCB1PTGER4CLK4
SCHEMBL20114541 0.92 PTGER4 (0.39) ALDH1A3ABCG2ABCB1PTGER4CLK4
SCHEMBL22268467 0.92 PTGER4 (0.39) ALDH1A3ABCG2ABCB1MYCPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3392247-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-29 EP disclosed