Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229706 | 0.92 | S1PR1 (0.41) | S1PR1PRCPCPT1A | |
| SCHEMBL2226920 | 0.92 | S1PR1 (0.38) | S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL15021796 | 0.92 | S1PR1 (0.38) | S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL2226618 | 0.90 | S1PR1 (0.36) | S1PR1PRCPCPT1A | |
| SCHEMBL2224866 | 0.90 | HCRTR1 (0.34) | S1PR1 | |
| SCHEMBL2226748 | 0.90 | S1PR1 (0.33) | S1PR1CPT1A | |
| SCHEMBL2229207 | 0.89 | S1PR1 (0.51) | S1PR1PRCPCPT1AALDH1A1 | |
| SCHEMBL2226520 | 0.89 | S1PR1 (0.34) | S1PR1PPARGPPARACPT1A | |
| SCHEMBL2229532 | 0.88 | S1PR1 (0.40) | S1PR1PRCPCPT1AALDH1A1LMNA | |
| SCHEMBL14798831 | 0.85 | S1PR1 (0.50) | S1PR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523959-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-11-27 | — | — | EP | claimed |
| EP-2523959-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | claimed |
| WO-2011086078-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | claimed |
| EP-2523959-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-11-27 | — | — | EP | disclosed |