Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | CPT1A | P50416 | 12/20 | 0.33 |
| ▸ | CPT2 | P23786 | 8/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229706 | 0.94 | S1PR1 (0.41) | S1PR1CPT1ACPT2CPT1BPRCP | |
| SCHEMBL2229203 | 0.92 | S1PR1 (0.51) | S1PR1CPT1ACPT2CPT1BFFAR1 | |
| SCHEMBL15021694 | 0.92 | S1PR1 (0.51) | S1PR1CPT1ACPT2CPT1BFFAR1 | |
| SCHEMBL2229532 | 0.90 | S1PR1 (0.40) | S1PR1CPT1ACPT2CPT1BALDH1A1 | |
| SCHEMBL2226922 | 0.89 | S1PR1 (0.37) | S1PR1CPT1AALDH1A1PRCP | |
| SCHEMBL2226618 | 0.87 | S1PR1 (0.36) | S1PR1CPT1ACPT2PRCP | |
| SCHEMBL2226520 | 0.86 | S1PR1 (0.34) | S1PR1CPT1A | |
| SCHEMBL15310194 | 0.85 | S1PR1 (0.71) | S1PR1CPT1ACPT2CYP1A2ALDH1A1 | |
| SCHEMBL15021696 | 0.85 | S1PR1 (0.42) | S1PR1CPT1ACPT2CPT1B | |
| SCHEMBL2229703 | 0.85 | S1PR1 (0.42) | S1PR1CPT1ACPT2CPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523959-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-11-27 | — | — | EP | claimed |
| EP-2523959-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | claimed |
| WO-2011086078-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | claimed |
| EP-2523959-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-11-27 | — | — | EP | disclosed |