Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | MGLL | Q99685 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486309 | 0.91 | PTGS1 (0.38) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL10018581 | 0.88 | MGLL (0.38) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL14655039 | 0.87 | PTGS1 (0.40) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL15892729 | 0.87 | PTGS1 (0.36) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL15892740 | 0.84 | MGLL (0.35) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL15892731 | 0.83 | PTGS1 (0.33) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL10018579 | 0.82 | MGLL (0.33) | PTGS1PTGS2MGLLFAAHPOLB | |
| SCHEMBL20470971 | 0.82 | KAT2A (0.39) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL15895109 | 0.82 | PTGS1 (0.36) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL12201716 | 0.81 | KAT2A (0.39) | PTGS1PTGS2MGLLFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050233950-A1 | Synergistic antimicrobial compositions and methods for reducing biofilm formation | PIVOT FINANCIAL INC. (CA) | 2005-10-20 | — | — | US | claimed |
| WO-2005094579-A1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS AND METHODS FOR REDUCING BIOFILM FORMATION | KANE BIOTECH INC. (CA) | 2005-10-13 | — | — | WO | claimed |
| JP-2907474-B2 | — | — | 1999-06-21 | — | — | JP | claimed |
| WO-1999011701-A1 | METHODS OF USING A BUTYLUREA GEL COMPOSITION FOR THE TREATMENT AND PREVENTION OF INFECTIONS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) | 1999-03-11 | — | — | WO | claimed |
| EP-0439540-B1 | ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED FC REGIONS | 3I RES EXPL LTD (GB) | 1995-06-28 | — | — | EP | claimed |
| EP-0596011-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1994-05-11 | — | — | EP | claimed |
| WO-1993002105-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1993-02-04 | — | — | WO | claimed |
| EP-0439540-A1 | ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED FC REGIONS. | 3I RES EXPL LTD (GB) | 1991-08-07 | — | — | EP | claimed |
| WO-1990004413-A1 | ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED Fc REGIONS | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1990-05-03 | — | — | WO | claimed |
| WO-2023112443-A1 | HEAT-CURABLE COMPOSITION, ADHESIVE SHEET, PRINTED WIRING BOARD, AND ELECTRONIC APPLIANCE | 東洋インキＳＣホールディングス株式会社 | 2023-06-22 | — | — | WO | disclosed |
| WO-2023008186-A1 | ADHESIVE RESIN SHEET, PRINTED WIRING BOARD, AND ELECTRONIC DEVICE | 東洋インキＳＣホールディングス株式会社 | 2023-02-02 | — | — | WO | disclosed |
| EP-2087910-B1 | Polymeric prodrugs | ASCENDIS PHARMA GMBH (DE) | 2022-05-04 | — | — | EP | disclosed |
| US-11191811-B2 | Osteocalcin as a treatment for frailty associated with aging | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-12-07 | — | — | US | disclosed |
| US-20210283264-A1 | Polymeric Prodrugs with a Self-Immolative Linker | ASCENDIS PHARMA GMBH (DE) | 2021-09-16 | — | — | US | disclosed |
| EP-0453082-A1 | Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent | HYBRITECH INCORPORATED (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0446071-A2 | Tris-maleimido compounds as intermediates in trifunctional antibody synthesis | HYBRITECH INCORPORATED (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0439540-A1 | ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED FC REGIONS. | 3I RES EXPL LTD (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0429611-A1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | Roche Diagnostics GmbH (DE) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990015798-A1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-12-27 | — | — | WO | disclosed |
| WO-1990004413-A1 | ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED Fc REGIONS | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1990-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283264-A1 | Polymeric Prodrugs with a Self-Immolative Linker | PAICS, MPI, GPI | PTGS1 2147/4885PTGS2 2566/4885MGLL 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.