SCHEMBL2227136

SCHEMBL2227136

CCCCCCCCCCCCCCCCCC(=O)C(O)CN

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.55
DNM1 Q05193 1/20 0.50
CES1 P23141 3/20 0.48
MEN1 O00255 1/20 0.47
FAAH O00519 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5393793 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL28339868 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL28430028 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL678577 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL27141492 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL5401819 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL31399648 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL16782313 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL10603119 1.00 CES2 (0.55) CES2DNM1CES1MEN1FAAH
SCHEMBL29945608 0.98 CES2 (0.53) CES2DNM1CES1MEN1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326708-A1 LONG-ACTING SPLEEN-TARGETING CATIONIC LIPID COMPOUND COMPRISING BENZENE RING STRUCTURE, COMPOSITION COMPRISING SAME, AND USE THEREOF BEIJING YOUCAREKECHUANG PHARMACEUTICAL TECH CO LTD (CN) 2025-10-23 US claimed
CN-115281192-B Preparation and method for improving photosynthetic efficiency and/or drought resistance of vegetable crops 海南浙江大学研究院 2024-10-08 CN claimed
CN-115281192-A Preparation and method for improving photosynthetic efficiency and/or drought resistance of vegetable crops 海南浙江大学研究院 2022-11-04 CN claimed
CN-110612119-A Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents 西雅图儿童医院(DBA西雅图儿童研究所) 2019-12-24 CN claimed
CN-109689045-A Purposes of the topical formulations of cannboid in treatment epidermolysis bollosa and Related connective tissue illness 因美制药公司 2019-04-26 CN claimed
CN-105191937-B Application of stearoyl ethanolamine in plant botrytis resistance improvement 浙江大学 2017-04-12 CN claimed
WO-2013063263-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN LYCUS LLC (US) 2013-05-02 WO claimed
CN-110612119-B Phosphatidylether (PLE) CAR T cell tumor targeting (CTCT) agents 西雅图儿童医院(DBA西雅图儿童研究所) 2024-10-29 CN disclosed
CN-115281192-B Preparation and method for improving photosynthetic efficiency and/or drought resistance of vegetable crops 海南浙江大学研究院 2024-10-08 CN disclosed
CN-115281192-B Preparation and method for improving photosynthetic efficiency and/or drought resistance of vegetable crops 海南浙江大学研究院 2024-10-08 CN disclosed
WO-2024062395-A1 USE OF 5-METHOXY-2-AMINOINDAN (\"MEAI\") IN METHODS FOR TREATING METABOLIC SYNDROME Clearmind Medicine Inc. (IL) 2024-03-28 WO disclosed
CN-117177989-A Activity-inducible fusion proteins with heat shock protein 90 binding domain 西雅图儿童医院以西雅图儿童研究机构名义经营 2023-12-05 CN disclosed
CN-117092238-A Endogenous cannabinoid biomarker composition, detection method and application thereof 上海中医药大学 2023-11-21 CN disclosed
CN-105191937-A Application of stearoyl ethanolamine in plant botrytis resistance improvement UNIV ZHEJIANG 2015-12-30 CN disclosed
CN-105191937-A Application of stearoyl ethanolamine in plant botrytis resistance improvement UNIV ZHEJIANG 2015-12-30 CN disclosed
CN-105191937-A Application of stearoyl ethanolamine in plant botrytis resistance improvement UNIV ZHEJIANG 2015-12-30 CN disclosed
WO-2013063263-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN LYCUS LLC (US) 2013-05-02 WO disclosed
WO-2011089240-A1 DIAGNOSTIC METHOD FOR ENDOMETRIAL RECEPTIVITY EQUIPO IVI INVESTIGACIÓN S.L. (ES) 2011-07-28 WO disclosed
EP-2146739-A2 METHODS OF IMMUNE OR HEMATOLOGICAL ENHANCEMENT, INHIBITING TUMOUR FORMATION OR GROWTH, AND TREATING OR PREVENTING CANCER, CANCER SYMPTOMS, OR THE SYMPTOMS OF CANCER TREATMENTS Fontera Co-Operative Group Limited (NZ) 2010-01-27 EP disclosed
WO-2008140335-A2 METHODS OF IMMUNE OR HEMATOLOGICAL ENHANCEMENT, INHIBITING TUMOUR FORMATION OR GROWTH, AND TREATING OR PREVENTING CANCER, CANCER SYMPTOMS, OR THE SYMPTOMS OF CANCER TREATMENTS FONTERRA CO-OPERATIVE GROUP LIMITED (NZ) 2008-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326708-A1 LONG-ACTING SPLEEN-TARGETING CATIONIC LIPID COMPOUND COMPRISING BENZENE RING STRUCTURE, COMPOSITION COMPRISING SAME, AND USE THEREOF CD47, MYD88, SGMS1 CES2 2384/4885DNM1 3190/4885CES1 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.