Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100069 | 0.88 | MAPT (0.52) | HDAC1MEN1MAPTKMT2ACHRNA7 | |
| SCHEMBL22272764 | 0.87 | PDGFRB (0.49) | HDAC1MEN1MAPTKMT2ACHRNA7 | |
| SCHEMBL22272704 | 0.87 | PDGFRB (0.53) | HDAC1MEN1MAPTKMT2APDGFRB | |
| SCHEMBL18574511 | 0.82 | MEN1 (0.47) | HDAC1MEN1MAPTKMT2APDGFRB | |
| SCHEMBL22718726 | 0.81 | HDAC1 (0.60) | HDAC1MEN1MAPTKMT2ALMNA | |
| SCHEMBL15697566 | 0.81 | MAPT (0.58) | HDAC1MEN1MAPTKMT2APTPN2 | |
| SCHEMBL15697561 | 0.81 | HDAC1 (0.74) | HDAC1MEN1MAPTKMT2APDGFRB | |
| Hydrochloric Acid SCHEMBL20239294 | 0.81 | MEN1 (0.46) | HDAC1MEN1MAPTKMT2APDGFRB | |
| SCHEMBL12501405 | 0.81 | MEN1 (0.55) | HDAC1MEN1MAPTKMT2APDGFRB | |
| SCHEMBL26725342 | 0.80 | MEN1 (0.52) | HDAC1MEN1MAPTKMT2APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020152462-A1 | PYRROLOBENZODIAZEPINE DERIVATIVES AS INHIBITORS OF NF-KAPPA B FOR THE TREATMENT OF PROLIFERATIVE DISEASES | KING'S COLLEGE LONDON (GB) | 2020-07-30 | — | — | WO | disclosed |