Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | POLR1A | O95602 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29779081 | 0.92 | USP30 (0.81) | USP30GABRA5GPR119POLBHPGDS | |
| SCHEMBL2227282 | 0.82 | USP30 (0.52) | USP30HIF1A | |
| SCHEMBL23019814 | 0.81 | USP30 (1.00) | USP30GPR119HPGDS | |
| SCHEMBL18123875 | 0.81 | USP30 (1.00) | USP30GPR119HPGDS | |
| SCHEMBL2282218 | 0.81 | USP30 (0.53) | USP30HIF1A | |
| SCHEMBL16973639 | 0.80 | USP30 (0.54) | USP30GABRA5POLR1APOLB | |
| SCHEMBL18124190 | 0.79 | USP30 (1.00) | USP30GABRA5POLBHPGDS | |
| SCHEMBL23019697 | 0.79 | USP30 (1.00) | USP30GABRA5POLBHPGDS | |
| SCHEMBL120242 | 0.79 | USP30 (0.64) | USP30GABRA5POLR1APOLB | |
| SCHEMBL28513447 | 0.77 | USP30 (0.70) | USP30GPR119HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091410-A1 | TRPV4 ANTAGONISTS | GLAXOS SMITHKLINE LLC (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011090812-A2 | PROCESSES FOR MAKING HIGH PURITY RENEWABLE SOURCE-BASED PLASTICIZERS AND PRODUCTS MADE THEREFROM | ARCHER DANIELS MIDLAND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011091410-A1 | TRPV4 ANTAGONISTS | GLAXOS SMITHKLINE LLC (US) | 2011-07-28 | — | — | WO | disclosed |