Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22272916 | 0.87 | TYK2 (0.56) | TYK2 | |
| SCHEMBL22252398 | 0.86 | TYK2 (0.59) | TYK2 | |
| SCHEMBL22252400 | 0.86 | TYK2 (0.59) | TYK2 | |
| SCHEMBL22252399 | 0.86 | TYK2 (0.59) | TYK2 | |
| SCHEMBL22252601 | 0.82 | TYK2 (0.77) | TYK2 | |
| SCHEMBL20689026 | 0.79 | TYK2 (0.60) | TYK2 | |
| SCHEMBL22272927 | 0.78 | TYK2 (0.43) | TYK2 | |
| SCHEMBL22273237 | 0.78 | TYK2 (0.50) | TYK2 | |
| SCHEMBL21227563 | 0.76 | TYK2 (0.68) | TYK2 | |
| SCHEMBL29754379 | 0.75 | TYK2 (0.78) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154474-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-07-30 | — | — | WO | disclosed |