Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 17/20 | 0.79 |
| ▸ | ABHD6 | Q9BV23 | 13/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | PLA2G7 | Q13093 | 7/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18064772 | 0.90 | MGLL (0.80) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL18064910 | 0.89 | MGLL (0.79) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL24309036 | 0.89 | MGLL (0.79) | MGLLABHD6CYP2D6PLA2G7 | |
| Elcubragistat SCHEMBL15100632 | 0.88 | MGLL (1.00) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL18064780 | 0.88 | MGLL (0.78) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL18064875 | 0.88 | MGLL (0.74) | MGLLABHD6CYP2D6PLA2G7 | |
| Elcubragistat SCHEMBL20168257 | 0.88 | MGLL (0.98) | MGLLABHD6CYP2D6PLA2G7 | |
| Elcubragistat SCHEMBL20166890 | 0.88 | MGLL (0.98) | MGLLABHD6CYP2D6PLA2G7 | |
| Elcubragistat SCHEMBL29430943 | 0.88 | MGLL (0.98) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL23349060 | 0.88 | MGLL (1.00) | MGLLABHD6CYP2D6PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154683-A1 | METHODS OF TREATING DISEASE WITH MAGL INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2020-07-30 | — | — | WO | disclosed |